COMPOSITION
Rafoxanide …………….……… …………………………..…… .. …… ... 3.00 g
Fenbendazole …………………………………… …… .. ……… ... …… 3.00 g
Excipient qs ……… .. ……………………………......……………… ..… 100 ml
PHARMACEUTICAL PROPERTIES
Fenbendazole is an anthelmintic from the benzimidazole family with great activity against gastrointestinal and pulmonary nematodes and on the taenia. Fenbendazole, like other benzimidazoles, works by inhibiting the polymerization of microtubilin, causing cell disorganization and death of the parasite by starvation. Fenbendazole is not active on fluke and oestras. While the action of rafoxanide is mainly directed against these parasites. Thus, the association of these two major anthelmintics forms a broad-spectrum product, active both on the digestive and respiratory strongles, on the moat and on the oestras. It should be noted that rafoxanide is also endowed with excellent activity on hematophagous nematodes. From a pharmacological point of view, fenbendazole is metabolized in the body into several metabolites including oxfendazole, which has great anthelmintic activity. While rafoxanide undergoes a very slow metabolism which increases its persistence in the body.
TARGET SPECIES
Sheep.
INDICATIONS
Treatment of internal parasitic diseases in the target species: Gastrointestinal and pulmonary nematodoses, moniosis, fascioliasis and oestrosis.
ADMINISTRATION AND DOSAGE
Oral use at a single dose of 7.5 mg / kg bodyweight, ie 2.5 ml / 10 kg bodyweight.
SIDE EFFECTS
If the recommended doses are observed, all components of RANIFEN are tolerated by the target species.
PRECAUTIONS FOR USE
- Respect the dose in females at the beginning of gestation. - Shake well before use. - Keep the product out of the reach of children.
WITHDRAWAL PERIOD
Meat and offal: 42 days.
STORAGE CONDITIONS
Keep the product in the original packaging, protect from light and at a temperature ≤ 25 ° C.
PRESENTATIONS
Bottles of 250 ml, 500 ml, 1 Liter ,and 5 Liter