Sheep

OVIMAX

COMPOSITION

Ivermectin …………...... ……............. …………….…………… ... 0.10 g
Triclabendazole …………............. ………………. ….............… 5.00 g
Albendazole ……………………….…...... ……… ........................ 2.50 g
Selenium (sf sodium selenite, 5H2O) ……………….… .,0.06 g
Cobalt (sf. sulfate) …………… .. ……………………… ............ 0.075 g
Excipient qs ……… .. ………………………………………....… ..… 100 ml

PHARMACEUTICAL PROPERTIES

Ivermectin, is an antiparasitic of the family of avermectins endowed with a great activity as well on the internal parasites as external of the domestic animals. Ivermectin acts on nematodes and arthropods via gamma amino-butyric acid (GABA). It causes its release from the presynaptic membrane and potentiates its binding to receptors located on the postsynaptic membrane. At the recommended doses, ivermectin is very well tolerated in both adults and young people and can be used at all stages of gestation. Triclabendazole, an anthelmintic from the benzimidazole family, is very active on the fluke at all stages of development. From a pharmacological point of view, triclabendazole is rapidly metabolized in the body to triclabendazole sulfoxide, responsible for the anthelmintic activity of this product. Albendazole is an anthelmintic from the benzimidazole family active on gastrointestinal and pulmonary nematodes, tapeworms and fluke (F. hepatica). Albendazole is active on both adult and larval forms of digestive nematodes. Albendazole is also ovicidal. In the body, albendazole is rapidly metabolized to several metabolites in which albendazole sulfoxide is as active as the parent product. The combination of the three products, ivermectin, triclabendazole and albendazole is complementary and makes it possible to cover all the internal parasites encountered in the target animals. Selenium is a trace element used for the fight against nutritional myopathies which are very common in sheep in Morocco. Cobalt is essential for the synthesis of vitamin B12 which plays a decisive role in hematopoiesis. This trace element will help alleviate the anemia problems inherent in blood-sucking worm infestation.

TARGET SPECIES

Sheep and goats.

INDICATIONS

Treatment of gastrointestinal and pulmonary nematodoses of estrosis, fluke and tapeworm in target species.

ADMINISTRATION AND DOSAGE

OVIMAX is recommended for oral administration in the single dose of 2.0 ml suspension / 10 kg bodyweight, corresponding to 0.20 mg ivermectin and 10 mg triclabendazole, 7.5 mg albendazole, 0.12 mg selenium and 0.15 mg cobalt per kilogram of bodyweight.

CONTRAINDICATIONS AND INTERACTIONS

OVIMAX is prohibited in dairy females whose milk or its derivatives are intended for human consumption and in dairy females 28 days before parturition.

SIDE EFFECTS

If the recommended doses are observed, all components of OVIMAX are tolerated by the target species.

PRECAUTIONS FOR USE